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Introduction to enzymatic bioconversions technology and engineering

Industrial bioconversions, enzyme kinetics, soluble and immobilized enzyme reactors technologies and operation, bioconversions cost

ONLINE COURSE: On-demand

COURSE FEE: 350 € per session

COURSE ORGANIZATION

Course organized in 3 sessions

Scheduling: suggested one session per week

Effort: 6 - 6 hours per session

COURSE DESCRIPTION

The course provides an introduction to enzymatic bioconversions processes. It describes the industrially used enzyme biocatalysts and bioconversion reactions, the kinetics of enzyme catalyzed reactions, the soluble and immobilized enzymes bioreactors  technologies and optimal operations. It also reviews the cost analysis of bioconversion processes.

INSTRUCTORS​

  • Isabelle CHEVALOT, Professor ENSAIA

  • Jean-Marc ENGASSER, BioProcess Digital

DIGITAL LEARNING​

  • Learning platform with course resources

  • Live or recorded slideshow presentations

  • Case studies on spreadsheet templates with guides and corrections

  • Online collective or one-to-one tutoring

COURSE PROGRAM

SESSION 1: ENZYMATIC BIOCONVERSIONS TECHNOLOGIES AND COST

  • Industrial bioconversion enzymes and reactions

  • Soluble enzymes bioreactors technologies and operation modes

  • Immobilized enzymes bioreactors technologies 

  • Enzymatic bioconversion costs: equipment, enzymes and labor contributions

SESSION 2: ​BIOCONVERSIONS KINETICS AND SIMULATION

  • Bioconversion kinetics with soluble and immobilized enzymes

  • Bioreactors dynamics governing phenomena: reaction, mass transfer, fluid flow 

  • Bioreactors simulation models for reactors scale-up and optimization

SESSION 3: ENZYMATIC BIOREACTORS OPTIMAL OPERATION

  • Batch or continuous bioreactors: influence of enzyme kinetics and cost

  • Soluble ot immobilized enzymes reactors: influence of enzyme stability and cost

  • Optimal bioreactor temperature for minimal bioconversion cost

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